Pearls from Dr. Susan Olender
OIs that affect the GI tract
- CD4 count < 200: Shigella, Campylobacter, Salmonella, E. coli, Yersinia, Norovirus
- CD4 count < 100: Esophageal candidiasis
- CD4 count < 50: MAC, CMV (more systemic infections), visceral KS
- All CD4 counts: C Diff
- Proctitis - HSV, HPV, Gonorrhea, Chlamydia
Posted 08/02/16 09:16:26 AM by Anna Krigel
- Microscopy with staining (often with Gomori methenamine silver stain) of an induced sputum specimen or BAL fluid is necessary as Pneumocystis cannot be cultured
- Beta-D-glucan assay (Fungitell) has been shown to have a sensitivity of 92% and specificity of 86% for detecting PCP
- Serum LDH has a high sensitivity for PCP but poor specificity
Posted 08/02/16 09:51:22 AM by Anna Krigel
Kaposi sarcoma management:
- All patients are recommended for antiretroviral therapy, though the initiation of ART has been associated with the progression of KS as part of IRIS
- Small skin lesions can be treated locally with intralesional vinblastine
- Systemic chemotherapy is typically with Doxil (pegylated liposomal doxorubicin) and used for disease with widespread skin involvement or symptomatic visceral involvement
Posted 08/02/16 10:09:55 AM by Anna Krigel
For further reading...
Posted 08/02/16 10:11:29 AM by Anna Krigel
Created by Christopher Kelly
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The information on the website does not constitute official guidelines except where explicitly stated.
It is not meant to replace the advice of a health professional.