Pearls from Dr. Elizabeth Verna

54 yo woman with elevated transaminases returning from the DR with acute HCV infection


  • Chronic vs. Acute HCV infection

    Posted 07/20/16 09:18:54 AM by Anna Krigel

  • Patterns seen on liver biopsy

    Posted 07/20/16 09:55:53 AM by Anna Krigel

  • IL28B genotype testing

    Posted 07/20/16 10:04:47 AM by Anna Krigel

  • Acute HCV infection

    Posted 07/20/16 10:26:58 AM by Anna Krigel

  • For further reading...

    AASLD and IDSA guidelines for diagnosis and management of HCV infection
    Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection

    Posted 07/20/16 10:28:21 AM by Anna Krigel

  • 52 y/o F hx of Chronic Hep B p/w acute flare of Hep B


  • Epidemiology of Hepatitis B infection

    Posted 01/10/17 10:34:37 AM by Ying Liu

  • Phases of Hepatitis B Infection

    Posted 01/10/17 10:35:45 AM by Ying Liu

  • Management of Chronic Hepatitis B infection

    Posted 01/10/17 10:39:52 AM by Ying Liu

  • NEJM: A comparison of Entecavir and Lamivudine for HBeAg-Positive Chronic Hepatitis B

    Posted 01/10/17 10:41:22 AM by Ying Liu

  • 63 yo man with history of IVDU presented to clinic with weight loss, found to have HCC with HCV positivity


  • ETOH drinking in patients with HCV increases the risk for advanced fibrosis ; advanced fibrosis in HCV increases the risk for HCC

    Posted 04/25/17 09:48:04 AM by Anna Krigel

  • HCC most commonly distantly metastasizes to the lungs and bones

    Posted 04/25/17 10:14:25 AM by Anna Krigel

  • Increased alkaline phosphatase out of proportion to transaminase or bilirubin elevation can be indicative of diseases that infiltrate the liver

    Posted 04/25/17 10:15:17 AM by Anna Krigel

  • HCC screening

    Posted 04/25/17 10:37:18 AM by Anna Krigel

  • Stages of hepatic fibrosis (METAVIR score)

    Posted 04/25/17 01:30:32 PM by Anna Krigel

  • Diagnosis of HCC - made on triple phase CT or MRI, radiologic imaging is characteristic of HCC if the lesion has "arterial enhancement with washout" on the venous phase

    Posted 04/25/17 01:35:38 PM by Anna Krigel

  • HCV treatment guidelines

    Posted 04/25/17 01:36:49 PM by Anna Krigel

  • For further reading...

    Treatment algorithm for HCC
    SHARP Trial (NEJM)

    Posted 04/25/17 01:39:36 PM by Anna Krigel

  • 48YO with HIV, hep C p/w RUQ pain found to have autoimmune hepatitis


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