Consider elective intubation for severe metabolic acidosis - don't wait until patient is hypotensive!
Bicarbonate traps salicylate outside cell and can help with metabolite clearance.
"Lactate gap": difference between indirect and direct measures of lactate (similar to osmolar gap)
- Ex. in cases of ethylene glycol ingestion, lactate will be elevated in indirect measurement (blood gas) but normal on direct measurement (blood chemistries)
NSAIDs usually cause acute tubular necrosis (ATN) when superimposed on another renal-compromising process (e.g. volume depletion, CKD, ACEi/ARB use)
NSAID-induced acute interstitial nephritis (AIN) generally presents with greater proteinuria than other causes of AIN
Posted 06/01/17 03:13:10 PM by Iheanacho (Obi) Emeruwa
Created by Christopher Kelly
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