Pearls from Dr. Andrew Bomback

80 yo F with new presentation of ANCA-associated rapidly progressive glomerulonephritis


  • RPGN = clinical syndrome of acute GN with progressive loss of renal function over a short period of time, characterized by extensive crescent formation

    Posted 09/01/16 11:17:55 AM by Anna Krigel

  • Initial therapy for RPGN

    Posted 09/01/16 11:23:58 AM by Anna Krigel

  • Options for maintenance therapy for ANCA-associated GN - can depend on PR3 vs MPO positivity (PR3 typically associated with more aggressive disease course, more responsive to treatment, and having a higher chance of recurrence)

    Posted 09/01/16 11:53:19 AM by Anna Krigel

  • For further reading...

    IMPROVE Trial

    Posted 09/01/16 11:54:20 AM by Anna Krigel

  • 35 y/o F hx of auto-immune dz who p/w RPGN found to have Anti-GBM disease


  • RPGN - Rapidly Progressive Acute Renal Failure (over weeks)
    Two ways to approach Differential
    Drugs like PPI unlikely to cause such a rapid change in Cr with interstitial nephritis 

    Posted 04/06/17 09:18:58 AM by Ying Liu

  • Clinical Pearls

    Posted 04/06/17 09:19:55 AM by Ying Liu

  • Rituxumab vs cyclophosphamide for ANCA and Anti-GBM Disease

    Posted 04/06/17 09:51:28 AM by Ying Liu

  • For further reading...

    Jones et al. 

    Posted 04/06/17 09:51:48 AM by Ying Liu

  • For further reading...

    Stone et al. 

    Posted 04/06/17 09:52:03 AM by Ying Liu

  • Hypertensive Emergencies and Urgency


    61yo M with Sjogren's p/w lower extremity weakness and swelling found to have ANCA-associated vasculitis


  • Evaluating acute kidney injury

    Causes of glomerulonephritis

    ANCA Vasculitis

    Posted 06/27/17 04:20:19 PM by Iheanacho (Obi) Emeruwa

  • 30YOM p/w HTN Emergency-->found to have Men2a


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