52yo F w/ SLE on long standing immunosuppressants who p/w pancytopenia of unclear etiology
Dr. Andrew Eisenberger | Morning Report | 05/23/2017
Prednisone for ITP with decrease production of anti-platelet antibodies. However, half life of IgG is 3 weeks, so immediate response to Prednisone is not this mechanism. Prednisone also decreases expression of FcGamma receptor, which leads to fast response seen with steroids. IVIG saturates the FcGamma receptor, which prevents opsonization of platelets coated with antibodies.
Posted 05/24/17 09:43:43 AM by Emily Miller
Hematologic Complications of Bariatric Surgery: B12 deficiency, Iron deficiency, Copper deficiency - causes dorsal column neuropathy, anemia and neutropenia.
Posted 05/24/17 09:45:40 AM by Emily Miller
A shortened PTT can be a risk factor for thrombosis. Can see with conditions that cause increased fibrinogen, factor VIII levels or von willebrand factor.