Asterixis - seen in many forms of organ failure with toxic metabolic encephalopathy, characterized by loss of postural tone rather than an active movement
Posted 05/04/17 10:06:15 AM by Anna Krigel
Monoclonal gammopathy, paraproteinemia
- monoclonal proteins produced by clonal plasma cells
- can get renal tissue deposition or precipitation of monoclonal immunoglobulin in the setting of AL amyloid, light chain proximal tubulopathy, and proliferative GN
- will see significant proteinuria but low amount of microalbumin (non-albumin proteinuria), indicating the presence of other proteins or paraproteins
Posted 05/04/17 10:27:22 AM by Anna Krigel
Bilateral enlargement of kidneys - usually indicative of an infiltrative disease like amyloidosis or lymphoma, or of IgG4-related disease
Posted 05/04/17 10:28:44 AM by Anna Krigel
- Renal cell carcinoma - ~90% of malignant neoplasms of the kidney, teaching point: RCC does not cause renal failure
- Renal cyst
- Metanephric adenoma
- Xanthogranulomatous pyelonephritis
Posted 05/04/17 10:31:22 AM by Anna Krigel
Primary renal lymphoma
- extremely rare and highly aggressive
- causes renal failure via infiltration of the renal parenchyma
- has been reported to be caused by many classes of non-Hodgkin lymphoma
- diagnosis made via renal biopsy
Posted 05/04/17 10:37:05 AM by Anna Krigel
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