• Asterixis - seen in many forms of organ failure with toxic metabolic encephalopathy, characterized by loss of postural tone rather than an active movement
  
  

  Posted 05/04/17 10:06:15 AM by Anna Krigel

• Monoclonal gammopathy, paraproteinemia
  • monoclonal proteins produced by clonal plasma cells
  • can get renal tissue deposition or precipitation of monoclonal immunoglobulin in the setting of AL amyloid, light chain proximal tubulopathy, and proliferative GN
  • will see significant proteinuria but low amount of microalbumin (non-albumin proteinuria), indicating the presence of other proteins or paraproteins
  
  

  Posted 05/04/17 10:27:22 AM by Anna Krigel

• Bilateral enlargement of kidneys - usually indicative of an infiltrative disease like amyloidosis or lymphoma, or of IgG4-related disease
  
  

  Posted 05/04/17 10:28:44 AM by Anna Krigel

• Renal Masses
  • Malignant
    • Renal cell carcinoma - ~90% of malignant neoplasms of the kidney, teaching point: RCC does not cause renal failure
    • Metastasis
    • Lymphoma
  • Benign
    • Renal cyst
    • Oncocytoma
    • Angiomyolipoma
    • Metanephric adenoma
    • Xanthogranulomatous pyelonephritis
  
  

  Posted 05/04/17 10:31:22 AM by Anna Krigel

• Primary renal lymphoma
  • extremely rare and highly aggressive
  • causes renal failure via infiltration of the renal parenchyma
  • has been reported to be caused by many classes of non-Hodgkin lymphoma
  • diagnosis made via renal biopsy
  
  

  Posted 05/04/17 10:37:05 AM by Anna Krigel

Created by Christopher Kelly
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It is not meant to replace the advice of a health professional.