• DDx Pancreatic Tumors
  • Exocrine
    • Ductal Adenocarcinoma (MAJORITY)
    • Serous cystic tumors
    • Mucinous cystic tumors
  • Endocrine
    • Insulinoma
    • Gastrinoma
    • Glucagonoma
    • VIPoma
    • Somatostatinoma
  • Metastases
  
  

  Posted 03/30/17 09:05:24 AM by Ying Liu

• Squamous Cell Carcinoma of the Lung
  • 30% of NSCLC
  • Located centrally in larger bronchi
  • More common in men than women
  • Strongly associated with smoking
  
  

  Posted 03/30/17 09:06:14 AM by Ying Liu

• Management:
  • Need tissue to test for driver mutations (EGFR/ALK/ROS1) but is less common in SCC
  • Test for PDL-1
  • Firstline treatment in metastatic disease is traditional chemotherapy (platinum doublet) vs. Immunotherapy (PD-1 inhibitor) depending on co-morbidities and functional status.
  
  

  Posted 03/30/17 09:11:14 AM by Ying Liu

• For further reading...

  N Engl J Med. 2015 Oct 22;373(17):1627-39
  
  

  Posted 03/30/17 09:10:02 AM by Ying Liu

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