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Pulmonary Hypertension - PASP >25 mmHg
- WHO Group 1: PAH (Idiopathic, Inherited, Drug induced, Associated with Connective Tissue Disease, HIV and Schistosomiasis)
- WHO Group 2: Associated with Left Heart Failure
- WHO Group 3: Associated with Lung Disease and Chronic Hypoxemia
- WHO Group 4: Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
- WHO Group 5: Miscellaneous
Posted 03/27/17 09:15:51 AM by Ying Liu
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Interstitial Lung Disease (ILD) Differential
- Known Causes
- Drugs - Amiodarone, Nitrofurantoin, Methotrexate
- Radiation
- Connective Tissue Disease (RA, Scleroderma, Sjogrens, less commonly SLE)
- Pneumoconiosis (Coal)
- Hypersensitivity Pneumonitis
- Idiopathic
- Idiopathic Pulmonary Fibrosis (IPF)
- Non-Specific Interstitial Pneumonia (NSIP)
- Respiratory Bronchiolitis ILD (RBILD) - smoking-related
- Cryptogenic Organizing Pneumonia (COP)
- Granulomatous (Sarcoid)
- Other (LAM, Pulmonary Alveolar Proteinosis (PAP), PUlmonary Langerhan's Cell Histiocytosis)
Posted 03/27/17 09:23:31 AM by Ying Liu
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Cryptogenic Organizing Pneumonia (COP)
- Rare, 1.1 per 100,000 people
- Characterized by proliferation of granulation tissue and fibroblasts in alveoli with intraluminal plugs of granulation tissue
- Present in 5th-6th decade of life
- Often presents with cough, dyspnea and occasionally fever
- Treatment is with glucocorticoids, and complete recovery occurs in two-thirds of patients treated with steroids. Recovery can be dramatic, occurring over 1-2 weeks
Posted 03/27/17 11:52:42 AM by Ying Liu
Created by Christopher Kelly
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