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Four items on initial evaluation of patient that indicate new diagnosis of ILD
- Subacute presentation
- Hypoxemia/impaired A-a gradient
- Diffuse lung lesions on CXR
- Restrictive pattern on PFTs
Posted 12/13/16 10:46:33 AM by Anna Krigel
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Sarcoidosis - nodular pattern in parenchyma on imaging as opposed to linear pattern
Posted 12/13/16 10:47:00 AM by Anna Krigel
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Restrictive Lung Disease
- Decreased Total Lung Capacity (TLC) on PFTs without evidence of obstruction on FEV1/FVC ratio
- Three causes
- Obesity
- ILD
- Neuromuscular disease
Posted 12/13/16 10:48:11 AM by Anna Krigel
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Four categories of Interstitial Lung Disease
- Rare - LAM, eosinophilic granuloma
- Known causes - Occupational exposures, environmental exposures, connective tissue diseases
- Granulomatous disease - sarcoidosis, hypersensitivity pneumonitis
- Idiopathic interstitial pneumonas
Posted 12/13/16 10:53:19 AM by Anna Krigel
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Idiopathic Interstitial Pneumonias
- Acute interstitial PNA (AIP) - acute (presentation of one month or less), idiopathic ARDS, very rare
- Respiratory bronchiolitis-ILD (RB-ILD), desquamative interstitial PNA (DIP) - smoking-related
- Cryptogenic organizing PNA (COP) - alveolar-filling process, mass-like and nodular in appearance
- Non-specific interstitial PNA (NSIP) - basilar-predominant process, ground glass opacities and reticular pattern on imaging, 80% of patients will have fibrotic pattern as well, seen in patients with undifferentiated connective tissue disease, SLE, Sjogren's, Systemic sclerosis, and dermatomyositis
- Usual interstitial PNA/Idiopathic pulmonary fibrosis (UIP/IPF) - basilar predominance, honey-combing pattern, seen in patients with RA
Posted 12/13/16 11:54:15 AM by Anna Krigel
Created by Christopher Kelly
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