• Cardiac sarcoidosis - most common clinical manifestations are heart block and arrhythmias
  
  

  Posted 12/05/16 10:28:47 AM by Anna Krigel

• Anticoagulants = one of the most common drug classes implicated in ER visits due to outpatient adverse drug events in 2013-2014 according to a recent paper in JAMA
  • Other drug classes most commonly implicated - antibiotics, diabetes agents, opioid analgesics
  
  

  Posted 12/05/16 10:32:41 AM by Anna Krigel

• Belatacept
  • Selective t-cell costimulation blocker
  • Used as maintenance immunosuppressive therapy after renal transplant in those who develop toxicity from calcineurin inhibitors (other option is sirolimus or everolimus)
  • Given intravenously as a monthly infusion
  • May increase the risk of posttransplant lymphoproliferative disorder
  
  

  Posted 12/05/16 10:50:26 AM by Anna Krigel

• Tzanck smear
  • Used to aid in the diagnosis of herpes virus, including herpes simplex, varicella, and zoster
  • Not used as commonly compared to the past due to the availability of immunofluorescence testing
  • Presence of multi-nucleated giant cells indicates infection with HSV or VZV
  
  

  Posted 12/05/16 10:58:13 AM by Anna Krigel

• For further reading...

  Phase III study of belatacept vs cyclosporine (BENEFIT study)
  US ED Visits for Outpatient Adverse Drug Events (JAMA)
  
  

  Posted 12/05/16 10:59:43 AM by Anna Krigel

Created by Christopher Kelly

Know a hypochondriac? Get them the best-selling book 'AM I DYING?!: A Complete Guide to Your Symptoms, and What to Do Next'
The information on the website does not constitute official guidelines except where explicitly stated.
It is not meant to replace the advice of a health professional.