Vedolizumab (integrin inhibitor, blocks leukocyte trafficking into GI mucosa) is a possibility but only approved for moderate disease
Posted 10/25/16 09:11:21 AM by Ying Liu
Indications for Colectomy
Massive GI bleeding
Acute Fulminant Colitis refractory to medical treatment
NOTE: Would scope and biopsy prior to surgery to confirm diagnosis as preferred surgery for UC is J-pouch to preserve rectal function, but this surgery is terrible for Crohn's. This is one instance where serologies have utility.
Posted 10/25/16 09:13:59 AM by Ying Liu
UC associated with PBC; can pick this up with elevated alkphos but not in acute setting
Proctitis does not affect CRC risk
Currently, no genetic screening recommendations for UC
Posted 10/25/16 09:14:59 AM by Ying Liu
Created by Christopher Kelly
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