- If >4cm, presumed to be malignant and needs further evaluation
- Need to consider whether it is functioning or not
Posted 10/10/16 11:45:56 AM by Adam Faye
Adrenal Mass - Must rule our Pheochromocytoma
- Serum Metanephrines have high sensitivity
- Do NOT start beta Blockers until Pheo is ruled out. Would not use alpha/beta blockers either, because generally block beta receptors more than alpha- leaving unopposed alpha blockade.
- Classic story from Pheo- often hear excessive diaphoresis
Posted 10/10/16 11:57:25 AM by Adam Faye
- Generally see hypertension and hypokalemia
- Labs generally show; suppressed Renin & Aldo >15. Typically Aldo/Renin ratio >20. Usually test AM sample, and have patient off mineralocorticoid receptor antagonists (eg: spironolactone) or ACEi/ARBs.
- Low K+ can cause aldosterone levels to appear lower
Posted 10/10/16 12:01:52 PM by Adam Faye
**Do NOT biopsy Adrenal Carcinoma, as it can seed other sites***
- Adjuvant Mitotine for treatment of adrenocrtical carcinoma may prolong recurrence-free survival
Posted 10/10/16 01:33:12 PM by Adam Faye
25% of one adrenal gland is all that is needed for normal functioning.
Posted 10/10/16 01:37:02 PM by Adam Faye
Posted 10/10/16 02:33:53 PM by Adam Faye
Created by Christopher Kelly
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