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NSAIDs Inhibit prostaglandin release (prostaglandins dilate the Afferent arteriole). Can cause:
- AIN
- ATN (especially with volume depletion)
- Papillary Necrosis
- Membranous/Minimal Change
Posted 10/06/16 10:56:13 AM by Adam Faye
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Nephritic: Injury/Inflammation of glomeruli which allows proteins, erythrocytes and leukocytes to pass through. Typical triad:
- Hypertension (abnormal bp regulation)
- Azotemia
- Red Cell Casts
Posted 10/06/16 10:59:22 AM by Adam Faye
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Glomerulonephritis Low Complement:
- SLE
- Post-infectious
- Endocarditis
- Cryogloublinemia
- MPGN
If normal complement GN
- Systemic - HSP, ANCA, Goodpasture's, vasculitis
- Renal only- Post-infectious GN, MPGN
Posted 10/06/16 11:05:44 AM by Adam Faye
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Acidosis in Renal Failure:
- Non-Gap: Ammoniagenesis is impaired
- Gap: Result of sulfate/phosphate buildup
Posted 10/06/16 11:06:43 AM by Adam Faye
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ESRD:
- Major cause of death is increased CV risk
- BP control is protective
- Data shows BP at HD is poor predictor of prognosis. Better to use home BP recordings
- Lipid data has been conflicting - this cochrane review showed little to no benefit in CV events
Posted 10/06/16 11:27:32 AM by Adam Faye
Created by Christopher Kelly
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The information on the website does not constitute official guidelines except where explicitly stated.
It is not meant to replace the advice of a health professional.