Differential for Respiratory Alkalosis
- CNS disorder altering the respiratory center
- Salicylate poisoning (particularly the early stage)
- Liver dysfunction/liver failure
- Severe anxiety
- Sepsis (effect of endotoxin release on the respiratory center)
Posted 09/29/16 11:50:00 AM by Anna Krigel
Compensatory Response to Respiratory Alkalosis
- Acute response - lowers HCO3 by 2 meq/L for every 10 mmHg decline in PCO2
- Chronic response (reduced PCO2 persistent for more than 3-5 days) - HCO3 level falls by 4 to 5 meq/L for every 10 mmHg reduction in PCO2
Posted 09/29/16 01:42:31 PM by Anna Krigel
Major consequence of alkalosis - hypokalemia
Consider higher level of care and possible intubation for management at pH>7.55
Posted 09/29/16 02:11:21 PM by Anna Krigel
- inhibits the activity of carbonic anhydrase
- produces both NaCl and NaHCO3 loss in the urine
- used as a diuretic in patient with volume overload and metabolic alkalosis
Posted 09/29/16 02:17:58 PM by Anna Krigel
For further reading...
Posted 09/29/16 02:24:34 PM by Anna Krigel
Created by Christopher Kelly
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