- destructive thyroiditis induced by an autoimmune mechanism
- more common in those with Hashimoto's
- can occur up to one year post-partum
- easy to miss as symptoms are sometimes mild and consistent with other post-partum symptoms like fatigue, weight changes, etc.
Posted 09/20/16 11:15:42 AM by Anna Krigel
Physical exam findings in hyperthyroidism/thyrotoxicosis
- anxious appearing, hyperactivity, rapid speech
- lid retraction, lid lag, exophthalomos, limited eye movement
- hyperreflexia (accelerated relaxation phase on reflex testing)
- pretibial myxedema
- poor attention
- goiter/neck fullness (if Grave's is the cause of thyrotoxicosis) with thyroid bruit (represents increased blood flow through the thyroid and active disease)
Posted 09/20/16 11:24:21 AM by Anna Krigel
Thyroid storm = severe, life-threatening symptoms in patients with thyrotoxicosis
- altered mentation
- cardiovascular dysfunction
Posted 09/20/16 11:26:59 AM by Anna Krigel
Management of thyrotoxicosis
- methimazole (or PTU if patient to be pregnant) -> decrease thyroid hormone synthesis, methimazole carries risk of agranulocytosis
- beta blockade -> symptom control
- iodine -> inhibit hormone release
- management hemodynamics -> IV fluids, steroids (decreases peripheral conversion of T4->T3, also for concomitant autoimmune adrenal insufficiency), cooling
Posted 09/20/16 11:34:14 AM by Anna Krigel
For further reading...
Posted 09/20/16 11:37:28 AM by Anna Krigel
Created by Christopher Kelly
The information on the website does not constitute official guidelines except where explicitly stated.
It is not meant to replace the advice of a health professional.