- destructive thyroiditis induced by an autoimmune mechanism
- more common in those with Hashimoto's
- can occur up to one year post-partum
- easy to miss as symptoms are sometimes mild and consistent with other post-partum symptoms like fatigue, weight changes, etc.
Posted 09/20/16 11:15:42 AM by Anna Krigel
Physical exam findings in hyperthyroidism/thyrotoxicosis
- anxious appearing, hyperactivity, rapid speech
- lid retraction, lid lag, exophthalomos, limited eye movement
- hyperreflexia (accelerated relaxation phase on reflex testing)
- pretibial myxedema
- poor attention
- goiter/neck fullness (if Grave's is the cause of thyrotoxicosis) with thyroid bruit (represents increased blood flow through the thyroid and active disease)
Posted 09/20/16 11:24:21 AM by Anna Krigel
Thyroid storm = severe, life-threatening symptoms in patients with thyrotoxicosis
- altered mentation
- cardiovascular dysfunction
Posted 09/20/16 11:26:59 AM by Anna Krigel
Management of thyrotoxicosis
- methimazole (or PTU if patient to be pregnant) -> decrease thyroid hormone synthesis, methimazole carries risk of agranulocytosis
- beta blockade -> symptom control
- iodine -> inhibit hormone release
- management hemodynamics -> IV fluids, steroids (decreases peripheral conversion of T4->T3, also for concomitant autoimmune adrenal insufficiency), cooling
Posted 09/20/16 11:34:14 AM by Anna Krigel
For further reading...
Posted 09/20/16 11:37:28 AM by Anna Krigel
Created by Christopher Kelly
Know a hypochondriac? Get them the best-selling book 'AM I DYING?!: A Complete Guide to Your Symptoms, and What to Do Next'
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